Biomedical Visuals

Northwestern HIV Latency


Discovery of a small molecule disruptor of PAF1C in transcription pause-release & HIV latency reversal

Purpose: A recent publication in Science Advances from the Simpson Querrey Institute for Epigenetics in the Shilatifard Laboratory describes the regulation of paused RNA Polymerase II in HIV latency reversal and the discovery of a possible small molecule disruptor in this process. Paper: https://www.science.org/doi/10.1126/sciadv.adf2468

Audience: General audience and Professionals in the field.

Date: 2023

Software: Autodesk 3dsMax, Vray, VMD, Pixologic Zbrush, PDB, Adobe Photoshop, Adobe Illustrator, and Adobe After Effects